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Article

Alveolar macrophages regulate the induction of primary cytotoxic T-lymphocyte responses during influenza virus infection.

Journal of virology - 1 Dec 1997

Wijburg O L, DiNatale S, Vadolas J, van Rooijen N, Strugnell R A

Abstract excerpt

Virus-specific cytotoxic T lymphocytes (CTL) are thought to be responsible for the eradication of respiratory influenza virus infections by direct cytolysis of virus-infected epithelial cells. In this study, we provide evidence for a role for alveolar macrophages (AM) in the regulation of pulmonary virus-specific CTL responses. Prior to infection with influenza virus, AM were selectively eliminated in vivo with a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9371606
DOI: 10.1128/JVI.71.12.9450-9457.1997
PMCID: PMC230250

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MLN

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Source receipt: pubmed, retrieved 7 Sept 2026.

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