Alveolar macrophages regulate the induction of primary cytotoxic T-lymphocyte responses during influenza virus infection.

doi:10.1128/JVI.71.12.9450-9457.1997

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Article

Alveolar macrophages regulate the induction of primary cytotoxic T-lymphocyte responses during influenza virus infection.

Journal of virology - 1 Dec 1997

Wijburg O L, DiNatale S, Vadolas J, van Rooijen N, Strugnell R A

Abstract excerpt

Virus-specific cytotoxic T lymphocytes (CTL) are thought to be responsible for the eradication of respiratory influenza virus infections by direct cytolysis of virus-infected epithelial cells. In this study, we provide evidence for a role for alveolar macrophages (AM) in the regulation of pulmona...

Topics

Animals
Influenza A virus
Kinetics
Leukocyte Count
Liposomes
Lung
Lymph Nodes
Macrophages, Alveolar
Male
Mice
Mice, Inbred BALB C
Orthomyxoviridae Infections
Phenotype
T-Lymphocytes, Cytotoxic

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