Article
Prevalence of the T215Y mutation in human immunodeficiency virus type 1-infected pregnant women in a New York cohort, 1995--1999.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Jul 2001
Sitnitskaya Y, Rochford G, Rigaud M, Essajee S, Pollack H, Krasinski K, Borkowsky W
Abstract excerpt
From 1997 through 1999, the prevalence of the zidovudine resistance mutation T215Y was 9.7% among pregnant women, and the human immunodeficiency virus type 1 (HIV-1) load in those with resistant virus was higher than that measured in women with wild-type HIV-1. All mutations were noted in women with zidovudine experience, which suggests that monotherapy may not be adequate prophylaxis for vertical transmission of...
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