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Article

A schizophrenia-susceptibility locus at 6q25, in one of the world's largest reported pedigrees.

American journal of human genetics - 1 Jul 2001

Lindholm E, Ekholm B, Shaw S, Jalonen P, Johansson G, Pettersson U, Sherrington R, Adolfsson R, Jazin E

Abstract excerpt

We have completed a genome scan of a 12-generation, 3,400-member pedigree with schizophrenia. Samples from 210 individuals were collected from the pedigree. We performed an "affecteds-only" genome-scan analysis using 43 members of the pedigree. The affected individuals included 29 patients with schizophrenia, 10 with schizoaffective disorders, and 4 with psychosis not otherwise specified. Two sets of...

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PMID: 11389481
DOI: 10.1086/321288
PMCID: PMC1226052

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