Article
Suggestive evidence for a schizophrenia susceptibility locus on chromosome 6q and a confirmation in an independent series of pedigrees.
Genomics - 1 Jul 1997
Cao Q, Martinez M, Zhang J, Sanders A R, Badner J A, Cravchik A, Markey C J, Beshah E, Guroff J J, Maxwell M E, Kazuba D M, Whiten R, Goldin L R, Gershon E S, Gejman P V
Abstract excerpt
We have investigated whether there is a locus on chromosome 6 that confers an increased susceptibility to schizophrenia using a two-stage approach and nonparametric linkage analysis. Allele sharing identical by descent (IBD) and multipoint maximum likelihood score (MLS) statistics were employed. Results from two tested data sets, a first data set, or genome scanning data set, and a second replication data set,...
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