Article
Linkage analysis of a large Swedish kindred provides further support for a susceptibility locus for schizophrenia on chromosome 6p23.
American journal of medical genetics - 20 Aug 1999
Lindholm E, Ekholm B, Balciuniene J, Johansson G, Castensson A, Koisti M, Nylander P O, Pettersson U, Adolfsson R, Jazin E
Abstract excerpt
Several reports have indicated genetic linkage between markers on the short arm of chromosome 6 and schizophrenia. However, significant threshold levels were not always achieved, and the chromosomal regions identified are large and different in different families. One way to decrease the problem of heterogeneity is to study a single extended pedigree. Here we report the analysis of a very large, previously...
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