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Article

Mutations in Cdh23 cause nonsyndromic hearing loss in waltzer mice.

Genomics - 1 Jun 2001

Wilson S M, Householder D B, Coppola V, Tessarollo L, Fritzsch B, Lee E C, Goss D, Carlson G A, Copeland N G, Jenkins N A

Abstract excerpt

Mutations at the waltzer (v) locus result in deafness and vestibular dysfunction due to degeneration of the neuroepithelium within the inner ear. Here, we use a positional cloning approach to show that waltzer encodes a novel cadherin (Cdh23), which is most closely related to the Drosophila Fat protein. A single nucleotide deletion in the v(J) allele and a single nucleotide insertion in the v allele are predicted...

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Source

Identifiers

PMID: 11386759
DOI: 10.1006/geno.2001.6554

Genes

CDH23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in Cdh23 cause nonsyndromic hearing loss in waltzer mice.PMID 11386759Read ↗

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