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Article

Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development.

Developmental biology - 15 Apr 2005

Lagziel Ayala, Ahmed Zubair M, Schultz Julie M, Morell Robert J, Belyantseva Inna A, Friedman Thomas B

Abstract excerpt

Mutant alleles of the gene encoding cadherin 23 are associated with Usher syndrome type 1 (USH1D), isolated deafness (DFNB12) in humans, and deafness and circling behavior in waltzer (v) mice. Stereocilia of waltzer mice are disorganized and the kinocilia misplaced, indicating the importance of cadherin 23 for hair bundle development. Cadherin 23 was localized to developing stereocilia and proposed as a component...

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Identifiers

PMID: 15882574
DOI: 10.1016/j.ydbio.2005.01.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development.PMID 15882574Read ↗

Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D.Semantic proximity Read ↗

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MAGI-1, A Candidate Stereociliary Scaffolding Protein, Associates with the Tip-Link Component Cadherin 23Semantic proximity Read ↗

Expression of the human usherin c.2299delG mutation leads to early-onset auditory loss and stereocilia disorganization.Semantic proximity Read ↗

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