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Article

Analysis of MTH1 gene function in mice with targeted mutagenesis.

Mutation research - 2 Jun 2001

Tsuzuki T, Egashira A, Kura S

Abstract excerpt

Oxidative DNA damage is thought to contribute to carcinogenesis, ageing, and neurological degeneration. Further, the cumulative risk of cancer increases dramatically with age in humans. In general terms, cancer can be regarded as a degenerative disease of ageing. There is evidence for the accumulation of oxidative DNA damage with age based on studies mainly measuring an increase in 8-oxoguanine....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 11376688
DOI: 10.1016/s0027-5107(01)00108-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of MTH1 gene function in mice with targeted mutagenesis.PMID 11376688Read ↗

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