Article
Roche investigators say Invirase does not cause cross-resistance to other protease inhibitors.
BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation - 1 Sept 1995
Baker R
Abstract excerpt
New data presented at the Fourth HIV Drug Resistance Workshop in Italy suggest that treatment with Invirase (saquinavir) does not cause cross-resistance to other protease inhibitors, including Merck, Abbott, and Vertex compounds. In addition, HIV resistance to Invirase develops at a slower rate than seen with all other anti-HIV drugs, even after prolonged combination therapy with Invirase plus AZT. Data indicate...
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