Article
Association between ICAM-1 Gly-Arg polymorphism and renal parenchymal scarring following childhood urinary tract infection.
International journal of immunogenetics - 1 Feb 2006
Gbadegesin R A, Cotton S A, Watson C J, Brenchley P E C, Webb N J A
Abstract excerpt
Renal parenchymal scarring (RPS) following urinary tract infection (UTI) is an important cause of renal morbidity in children. Studies have shown that the intensity of the inflammatory response following infection is related to the risk of RPS. However, genetic variability in this response has not been studied. Adhesion molecules play a crucial role in leucocyte recruitment following infection, and polymorphisms...
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