Article
Maternal leptin receptor gene variant Gln223Arg is not associated with variation in birth weight or maternal body mass index in UK and South Asian populations.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 May 2001
Rand L, Winchester E C, Millwood I Y, Penny M A, Kessling A M
Abstract excerpt
BACKGROUND: Leptin is an adipocyte secreted hormone involved in regulation of body weight and metabolism in man. Placenta leptin levels correlate positively with birth weight. It is therefore possible that variation in the leptin receptor gene (LEPR) may contribute to obesity and influence birth weight. OBJECTIVE: This study investigates the influence of the leptin receptor gene variant Gln223Arg (A-->G, 668), on...
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