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Article

Fetal and maternal peroxisome proliferator-activated receptor gamma2 Pro12Ala does not influence birth weight.

Obesity (Silver Spring, Md.) - 1 Nov 2006

Pfab Thiemo, Poralla Christine, Richter Claus-Michael, Godes Michael, Slowinski Torsten, Priem Friedrich, Halle Horst, Hocher Berthold

Abstract excerpt

The association between the peroxisome proliferator-activated receptor (PPAR)gamma2 Pro12Ala polymorphism and insulin resistance is reported to depend on low birth weight. Low birth weight itself has been linked to type 2 diabetes and cardiovascular diseases in adulthood. We assessed whether the PPARgamma2 Pro12Ala polymorphism determines body size at birth and whether metabolic differences between the genotypes...

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Source

Identifiers

PMID: 17135601
DOI: 10.1038/oby.2006.218

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Fetal and maternal peroxisome proliferator-activated receptor gamma2 Pro12Ala does not influence birth weight.PMID 17135601Read ↗

The effects of the Pro12Ala polymorphism of the PPARgamma-2 gene on lipid metabolism interact with body size at birth.Semantic proximity Read ↗

Gene polymorphisms, size at birth, and the development of hypertension and type 2 diabetes.Semantic proximity Read ↗

The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth.Semantic proximity Read ↗

Effect of the Ala12 allele in the PPARgamma-2 gene on the relationship between birth weight and body composition in adolescents: the AVENA study.Semantic proximity Read ↗

A possible role for the PPARG Pro12Ala polymorphism in preterm birth.Semantic proximity Read ↗

Breast-feeding modifies the association of PPARgamma2 polymorphism Pro12Ala with growth in early life: the Generation R Study.Semantic proximity Read ↗

PPAR-gamma2 Pro12Ala polymorphism is associated with weight gain in women with gestational diabetes mellitus.Semantic proximity Read ↗

Interaction of maternal peroxisome proliferator-activated receptor gamma2 Pro12Ala polymorphism with fetal sex affects maternal glycemic control during pregnancy.Semantic proximity Read ↗

Genetic determinants of low birth weight.Semantic proximity Read ↗

The Pro12Ala polymorphism of the PPAR gamma 2 gene regulates weight from birth to adulthood.Semantic proximity Read ↗

Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood: a family-based studySemantic proximity Read ↗

No evidence that established type 2 diabetes susceptibility variants in the PPARG and KCNJ11 genes have pleiotropic effects on early growth.Semantic proximity Read ↗

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