Article
Structural requirements of Tom40 for assembly into preexisting TOM complexes of mitochondria.
Molecular biology of the cell - 1 May 2001
Rapaport D, Taylor R D, Käser M, Langer T, Neupert W, Nargang F E
Abstract excerpt
Tom40 is the major subunit of the translocase of the outer mitochondrial membrane (the TOM complex). To study the assembly pathway of Tom40, we have followed the integration of the protein into the TOM complex in vitro and in vivo using wild-type and altered versions of the Neurospora crassa Tom40 protein. Upon import into isolated mitochondria, Tom40 precursor proteins lacking the first 20 or the first 40 amino...
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