Article
Characterization of Neurospora crassa Tom40-deficient mutants and effect of specific mutations on Tom40 assembly.
The Journal of biological chemistry - 10 Jan 2003
Taylor Rebecca D, McHale Bryan J, Nargang Frank E
Abstract excerpt
The TOM complex (Translocase of the Outer mitochondrial Membrane) is responsible for the recognition of mitochondrial preproteins synthesized in the cytosol and for their translocation across or into the outer mitochondrial membrane. Tom40 is the major component of the TOM complex and forms the translocation pore. We have created a tom40 mutant of Neurospora crassa and have demonstrated that the gene is essential...
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