Article
Kinetic properties of Streptococcus pneumoniae hyaluronate lyase.
Glycobiology - 1 Apr 2001
Kelly S J, Taylor K B, Li S, Jedrzejas M J
Abstract excerpt
Streptococcus pneumoniae hyaluronate lyase is a surface antigen of this bacterial pathogen, which causes significant mortality and morbidity in human populations worldwide. The primary function of this enzyme is the degradation of hyaluronan, a major component of the extracellular matrix of the tissues of practically all vertebrates. The enzyme uses a processive mode of action to degrade hyaluronan to a final...
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