Article

Rolipram and Pentoxifylline Combination Ameliorates Experimental Diabetic Neuropathy Through Inhibition of Oxidative Stress and Inflammatory Pathways in the Dorsal Root Ganglion Neurons

2022-01-10

Abstract excerpt

<title>Abstract</title> <p>Diabetic neuropathy (DN) is the most challenging microvascular complication of diabetes and there is no suitable treatment for it, so the development of new agents to relieve DN is urgently needed. Since oxidative stress and inflammation play an essential role in the development of DN, clearance of these factors are good strategies for the treatment of this disease. According to key rol...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a0381624-6b17-54aa-b553-6aace1cad548
DOI: 10.21203/rs.3.rs-1222680/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Rolipram and Pentoxifylline Combination Ameliorates Experimental Diabetic Neuropathy Through Inhibition of Oxidative Stress and Inflammatory Pathways in the Dorsal Root Ganglion NeuronsDOI 10.21203/rs.3.rs-1222680/v1Read

Pathological pathway and protective mechanisms of phytobioactives used in diabetic retinopathy: A reviewSemantic proximity Read

An optimized low-dose streptozotocin protocol enables rapid induction of diabetic neuropathy with high survival in ratsSemantic proximity Read

An optimized low-dose STZ model rapidly induces diabetic neuropathy in ratsSemantic proximity Read

[Pathogenesis of diabetic neuropathy].Semantic proximity Read

Pathophysiology and treatment of painful diabetic neuropathy.Semantic proximity Read

Sarsasapogenin ameliorates diabetes-associated memory impairment and neuroinflammation through inhibiting thrombin/PAR-1 pathwaySemantic proximity Read

Modulation of MAPK/Nrf2-HO1/Akt-eNOS/inflammasome pathways by morin in myocardial infarction in diabetic ratsSemantic proximity Read

Integrative Multiomic Analyses of Diabetic Neuropathic Pain in Dorsal Root Ganglia: Proteomics, Phospho-proteomics, and MetabolomicsSemantic proximity Read

Anti-Neuropathic Pain Activity of A Cationic Palladium (II) Dithiocarbamate By Suppressing The Inflammatory Mediators in Paclitaxel-Induced Neuropathic Pain ModelSemantic proximity Read

Expression of macrophage migration inhibitory factor in footpad skin lesions with diabetic neuropathy.Semantic proximity Read

Atorvastatin Alleviates Behavioral Symptoms in MPTP-lesioned Mice: Associated With NOX2-mediated Autophagy and Oxidative StressSemantic proximity Read