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Article

Contacts between the 5' nuclease of DNA polymerase I and its DNA substrate.

The Journal of biological chemistry - 10 Aug 2001

Xu Y, Potapova O, Leschziner A E, Grindley N D, Joyce C M

Abstract excerpt

The 5' nuclease of DNA polymerase I (Pol I) of Escherichia coli is a member of an important class of prokaryotic and eukaryotic nucleases, involved in DNA replication and repair, with specificity for the junction between single-stranded and duplex DNA. We have investigated the interaction of the 5' nuclease domain with DNA substrates from the standpoint of both the protein and the DNA. Phosphate ethylation...

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PMID: 11349126
DOI: 10.1074/jbc.M100985200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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