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Article

Disruption ofPlasmodium falciparumChitinase Markedly Impairs Parasite Invasion of Mosquito Midgut

1 Jun 2001

Abstract excerpt

To initiate invasion of the mosquito midgut, Plasmodium ookinetes secrete chitinolytic activity to penetrate the peritrophic matrix surrounding the blood meal. While ookinetes of the avian malaria parasite Plasmodium gallinaceum appear to secrete products of two chitinase genes, to date only one chitinase gene, PfCHT1, has been identified in the nearly completed Plasmodium falciparum strain 3D7 genome database....

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PMID: 11349075
DOI: 10.1128/iai.69.6.4048-4054.2001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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