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PbCap380, a novel oocyst capsule protein, is essential for malaria parasite survival in the mosquito

2 Feb 2008

Abstract excerpt

An essential requisite for transmission of Plasmodium, the causative agent of malaria, is the successful completion of a complex developmental cycle in its mosquito vector. Of hundreds of ookinetes that form in the mosquito midgut, only few transform into oocysts, a loss attributed to the action of the mosquito immune system. However, once oocysts form, they appear to be resistant to mosquito defences. During...

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PMID: 18248630
DOI: 10.1111/j.1462-5822.2008.01127.x

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