Article
Disruption of Plasmodium sporozoite transmission by depletion of sporozoite invasion-associated protein 1.
Eukaryotic cell - 1 Apr 2009
Engelmann Sabine, Silvie Olivier, Matuschewski Kai
Abstract excerpt
Accumulation of infectious Plasmodium sporozoites in Anopheles spp. salivary glands marks the final step of the complex development of the malaria parasite in the insect vector. Sporozoites are formed inside midgut-associated oocysts and actively egress into the mosquito hemocoel. Traversal of the salivary gland acinar cells correlates with the sporozoite's capacity to perform continuous gliding motility. Here,...
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