Article
Mixed Phenotype Acute Leukemia with t(12;17)(p13;q21)/TAF15-ZNF384 and Other Chromosome Abnormalities.
Cytogenetic and genome research - 1 Jan 2016
Yamamoto Katsuya, Kawamoto Shinichiro, Mizutani Yu, Yakushijin Kimikazu, Yamashita Tomoe, Nakamachi Yuji, Kawano Seiji, Hayashi Yoshitake, Matsuoka Hiroshi, Minami Hironobu
Abstract excerpt
The t(12;17)(p13;q11∼21) translocation is a very rare but recurrent cytogenetic aberration observed predominantly in early pre-B acute lymphoblastic leukemia (ALL) with CD19+CD10-CD33+ phenotype. This translocation was shown to form a fusion gene between TAF15 at 17q12 and ZNF384 at 12p13. On the other hand, der(1;18)(q10;q10) has been detected as a rare unbalanced whole-arm translocation leading to trisomy 1q in...
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