Article
A variant t(8;10;21) in a patient with pathological features mimicking atypical chronic myeloid leukemia.
Cancer genetics and cytogenetics - 1 May 2005
Lee Jiyun, Kern William F, Cain Joan B, Mulvihill John J, Li Shibo
Abstract excerpt
We report the case of an 11-year-old girl who was initially diagnosed with a chronic myeloproliferative disorder, possibly chronic myelogenous leukemia (CML), based on laboratory and blood and marrow morphological findings. The patient's high leukocyte count did not respond to hydroxyurea, a standard initial therapy for CML. Chromosomal analysis revealed that the patient did not have t(9;22), but a complex...
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