Article
Philadelphia-chromosome-positive, monosomy 7 biphenotypic acute mixed lineage leukemia in adults: a pluripotent stem cell disorder.
Leukemia - 1 Nov 1993
Hamaguchi H, Nakamura Y, Nagata K, Shiba S, Arimura H, Muroga K, Miyake S, Ohkawa Y, Morio T
Abstract excerpt
Two adult patients with acute mixed lineage leukemia (AMLL) having combined Philadelphia chromosome (Ph1) positivity and monosomy 7 are presented. The phenotypes of leukemic blasts from both cases were almost same (early B-lymphoid lineage and myeloid lineage); CD10+, CD13+, CD19+. HLA-DR+, and d...
Topics
- Acute Disease
- Antigens, CD
- Antigens, Differentiation, Myelomonocytic
- Burkitt Lymphoma
- CD13 Antigens
- Cell Transformation, Neoplastic
- Chromosome Fragility
- Chromosomes, Human, Pair 7
- Gene Rearrangement
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Hematopoietic Stem Cells
- Humans
- Immunophenotyping
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive