Article
Impact of sulfonylurea receptor 1 genetic variability on non-insulin-dependent diabetes mellitus prevalence and treatment: a population study.
American journal of medical genetics - 1 Jun 2001
Meirhaeghe A, Helbecque N, Cottel D, Arveiler D, Ruidavets J B, Haas B, Ferrières J, Tauber J P, Bingham A, Amouyel P
Abstract excerpt
The high affinity sulfonylurea receptor 1 (SUR1) is involved in the metabolism of glucose in pancreatic beta-cells. We investigated the impact of the SUR1 intron 16-3t-->c polymorphism on non-insulin-dependent diabetes mellitus (NIDDM) prevalence in a large representative sample of French men and women, 35-64 years old, and explored potential relationships between the SUR1 intron 16 -t-->c polymorphism and...
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