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Article

ABCC8 polymorphisms are associated with triglyceride concentration in type 2 diabetics on sulfonylurea therapy.

Genetic testing and molecular biomarkers - 1 Aug 2012

Nikolac Nora, Simundic Ana-Maria, Saracevic Andrea, Katalinic Darko

Abstract excerpt

BACKGROUND: The failure of therapy with oral hypoglycemic drugs leads to not only poorly regulated glycemic status, but also dyslipidemia and increased body weight and body mass index (BMI). Sulfonylureas act as insulin secretagogues by binding to the sulfonylurea receptor (SUR-1) encoded by the gene ABCC8. The aim of this study was to explore whether there is an association of ABCC8 polymorphisms SUR1 exon 16...

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Share to ATP-Binding Cassette Transporters
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Potassium Channels, Inwardly Rectifying

Share to Receptors, Drug

Share to Sulfonylurea Compounds

Share to Sulfonylurea Receptors

Share to Triglycerides

Source

Identifiers

PMID: 22533711
DOI: 10.1089/gtmb.2011.0337

Genes

ABCC8

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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