Article
Combined therapy with interferon and ribavirin in chronic hepatitis C does not affect serum quasispecies diversity.
Digestive diseases and sciences - 1 May 2001
Sookoian S, Castaño G, Frider B, Cello J, Campos R, Flichman D
Abstract excerpt
Our aim was to investigate if interferon plus ribavirin has any effect on serum HCV quasispecies distribution and the relationship between diversity of HCV quasispecies and treatment response. In all, 21 patients were treated with interferon plus ribavirin for 48 weeks. The presence of HCV quasispecies was determined in serum samples at baseline and at the fourth week of treatment by SSCP analysis of the...
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