Article
Hypervariable region 1 of hepatitis C virus genome and response to interferon therapy.
Clinical chemistry and laboratory medicine - 1 Sept 2000
Grahovac B, Bingulac-Popović J, Vucelić B, Hrstić I, Ostojić R, Drazić V, Balija M, Grgicević D
Abstract excerpt
The relationship between the complexity of the hypervariable region 1 (HVR1) quasispecies of hepatitis C virus (HCV) and responsiveness to interferon-alpha (IFN) therapy was studied in patients with chronic hepatitis C. Twelve HCV-RNA-positive patients were treated daily with high dose IFN and ri...
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