Article
Host phenotype characteristics and MC1R in relation to early-onset basal cell carcinoma.
The Journal of investigative dermatology - 1 Apr 2012
Ferrucci Leah M, Cartmel Brenda, Molinaro Annette M, Gordon Patricia B, Leffell David J, Bale Allen E, Mayne Susan T
Abstract excerpt
Basal cell carcinoma (BCC) incidence is increasing, particularly among adults under the age of 40 years. Pigment-related characteristics are associated with BCC in older populations, but epidemiologic studies among younger individuals and analyses of phenotype-genotype interactions are limited. We examined self-reported phenotypes and melanocortin 1 receptor gene (MC1R) variants in relation to early-onset BCC....
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