Article
A glycosylphosphatidylinositol (GPI)-negative phenotype produced in Leishmania major by GPI phospholipase C from Trypanosoma brucei: topography of two GPI pathways.
The Journal of cell biology - 1 Mar 1994
Mensa-Wilmot K, LeBowitz J H, Chang K P, al-Qahtani A, McGwire B S, Tucker S, Morris J C
Abstract excerpt
The major surface macromolecules of the protozoan parasite Leishmania major, gp63 (a metalloprotease), and lipophosphoglycan (a polysaccharide), are glycosylphosphatidylinositol (GPI) anchored. We expressed a cytoplasmic glycosylphosphatidylinositol phospholipase C (GPI-PLC) in L. major in order...
Topics
- Animals
- Carbohydrate Sequence
- Glycosphingolipids
- Glycosylphosphatidylinositol Diacylglycerol-Lyase
- Glycosylphosphatidylinositols
- Intracellular Membranes
- Leishmania major
- Metalloendopeptidases
- Molecular Sequence Data
- Phenotype
- Phosphatidylinositol Diacylglycerol-Lyase
- Phosphoric Diester Hydrolases