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Article

The effects of wild-type and mutant HFE expression upon cellular iron uptake in transfected human embryonic kidney cells.

Biochimica et biophysica acta - 23 Apr 2001

Feeney G P, Worwood M

Abstract excerpt

In order to measure the effects of HFE (haemochromatosis) upon iron uptake, stable expression of wild-type and C282Y, H63D and S65C mutant HFE cDNA was established in HEK 293 cells. Control cells were transfected with empty vector. Expression of HFE mRNA and protein was detected in the cell lines transfected with HFE cDNA, but not in the control cell line. The ferritin concentration in wild-type cells cultured in...

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Source

Identifiers

PMID: 11336795
DOI: 10.1016/s0167-4889(01)00075-1

Genes

HFE

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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