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Article

A multilocus model of the genetic architecture of autoimmune thyroid disorder, with clinical implications.

American journal of human genetics - 1 Jun 2008

Vieland Veronica J, Huang Yungui, Bartlett Christopher, Davies Terry F, Tomer Yaron

Abstract excerpt

We report here a preliminary model of the genetic architecture of Autoimmune Thyroid Disorder (AITD). Using a flexible class of mathematical modeling techniques, applied to an established set of data and supplemented with information both from candidate-gene and genome-wide-association studies and from basic bioinformatics, we find strong statistical support for a model in which AITD is the result of "hits" along...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18485327
DOI: 10.1016/j.ajhg.2008.04.017
PMCID: PMC2427261

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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