Article
Analysis of the threshold liability model provides new understanding of causation in autoimmune diseases.
Medical hypotheses - 1 Jan 2004
Haegert D G
Abstract excerpt
Autoimmune diseases include a heterogeneous group of complex traits, the causes of which are essentially unknown. The threshold liability model is a hypothesis that has a significant influence on thinking about causation in these diseases. Here, I analyze this model and assess its utility in understanding causation in autoimmunity. According to the model, members of a population have a normal distribution of...
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