Article
Increased myocardial GRP94 amounts during sustained atrial fibrillation: a protective response?
Circulation - 1 May 2001
Vitadello M, Ausma J, Borgers M, Gambino A, Casarotto D C, Gorza L
Abstract excerpt
BACKGROUND: Structural and phenotypic changes of cardiomyocytes characterize atrial fibrillation. We investigated whether changes in the glucose-regulated protein GRP94, which is essential for cell viability, occur in the presence of chronic atrial fibrillation. METHODS AND RESULTS: Samples of fibrillating atrial myocardium obtained from both goat and human hearts were analyzed for GRP94 expression by an...
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