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Article

Expression of the fibroblast activation protein during mouse embryo development.

The International journal of developmental biology - 1 Apr 2001

Niedermeyer J, Garin-Chesa P, Kriz M, Hilberg F, Mueller E, Bamberger U, Rettig W J, Schnapp A

Abstract excerpt

Human Fibroblast Activation Protein (FAP), a member of the serine prolyl oligopeptidase family, is a type II cell surface glycoprotein that acts as a dual-specificity dipeptidyl-peptidase (DPP) and collagenase in vitro. Its restricted expression pattern in embryonic mesenchyme, in wound healing and in reactive stromal fibroblasts of epithelial cancers, has suggested a role for the FAP protease in extracellular...

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Identifiers

PMID: 11330865

Genes

FAP

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