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Mouse fibroblast‐activation protein

15 Jun 1998

Abstract excerpt

The human fibroblast-activation protein (FAP), a member of the serine protease family, was discovered as an inducible type-II cell-surface glycoprotein selectively expressed by reactive stromal fibroblasts of epithelial cancers and healing wounds. Antibodies directed against human FAP have a clinical use for antibody-based tumor imaging. As part of an effort to generate animal models of FAP expression in...

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PMID: 9688278
DOI: 10.1046/j.1432-1327.1998.2540650.x

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