Article
Context-dependent and invariant associations between APOE genotype and levels of lipoproteins and risk of ischemic heart disease: a review.
Scandinavian journal of clinical and laboratory investigation. Supplementum - 1 Jan 2000
Frikke-Schmidt R
Abstract excerpt
Apolipoprotein E (APOE) plays a pivotal role in the catabolism of triglyceride-rich lipoproteins by serving as a ligand for lipoprotein receptors. The common three-allele (epsilon 2/epsilon 3/epsilon 4) variation in the APOE gene is the most studied susceptibility polymorphism to date, identified in more than 50 different populations worldwide. Differences in the associations between APOE genotype and lipids,...
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