Article
Biochemical and genetic studies on mouse aldehyde dehydrogenases.
Alcohol (Fayetteville, N.Y.) - 1 Jan 2000
Holmes R S, Algar E M, Mather P B
Abstract excerpt
Aldehyde dehydrogenase (AHD) exists as isozymes which are differentially distributed among tissues and subcellular fractions of mouse tissues. Genetic variants for liver mitochondrial (AHD-1) and cytoplasmic (AHD-2) isozymes have been used to map the responsible loci (Ahd-1 and Ahd-2) on chromosomes 4 and 19 respectively. Evidence for a regulatory locus (Ahd-3r) controlling the inducibility of the mouse liver...
Topics
- Aldehyde Dehydrogenase
- Animals
- Chromosome Mapping
- Cytosol
- Isoenzymes
- Male
- Mice
- Mice, Inbred Strains
- Mitochondria, Liver
- Phenotype
- Stomach
- Testis
