Article
Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations.
Journal of virology - 1 May 2001
Krieger N, Lohmann V, Bartenschlager R
Abstract excerpt
Studies of the Hepatitis C virus (HCV) replication cycle have been made possible with the development of subgenomic selectable RNAs that replicate autonomously in cultured cells. In these replicons the region encoding the HCV structural proteins was replaced by the neomycin phosphotransferase gen...
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