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Article

Mutations in hepatitis C virus RNAs conferring cell culture adaptation.

Journal of virology - 1 Feb 2001

Lohmann V, Körner F, Dobierzewska A, Bartenschlager R

Abstract excerpt

As an initial approach to studying the molecular replication mechanisms of hepatitis C virus (HCV), a major causative agent of acute and chronic liver disease, we have recently developed selectable self-replicating RNAs. These replicons lacked the region encoding the structural proteins and instead carried the gene encoding the neomycin phosphotransferase. Although the replication levels of these RNAs within...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11152517
DOI: 10.1128/JVI.75.3.1437-1449.2001
PMCID: PMC114050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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