Article
Nitric oxide modulates the angiogenic phenotype of middle-T transformed endothelial cells.
The international journal of biochemistry & cell biology - 1 Apr 2001
Morbidelli L, Donnini S, Mitola S, Ziche M
Abstract excerpt
The role of nitric oxide (NO) in the induction of angiogenesis was evaluated in a murine heart endothelioma cell line (H.end.FB) carrying the mT oncogene. Two clonal derivatives of H.end.FB, H80 and H73, exhibiting different NO synthase (NOS) activities were selected and used in the study. The relationship among NOS activity and tumor cell behaviour (growth, and angiogenic capacity) and the molecular control of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.