Article

Autoantigenic properties of the aminoacyl tRNA synthetase family in idiopathic inflammatory myopathies

2022-06-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Autoantibodies are thought to play a key role in the pathogenesis of idiopathic inflammatory myopathies (IIM). However, up to 40% of IIM patients, even those with clinical manifestations of anti-synthetase syndrome (ASSD), test seronegative to all known myositis-specific autoantibodies (MSAs). We hypothesized the existence of new potential autoantigens among human cytoplasmi...

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Literature Corpus work: 1ff38948-0da3-5a71-b007-76597a2697ea
DOI: 10.1101/2022.06.13.495951

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