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Article

Clinical and Pathological Features of Ovarian Cancer in Women with Germ-Line Mutations of<i>BRCA1</i>

7 Nov 1996

Abstract excerpt

BACKGROUND: We tested the hypothesis that ovarian cancers associated with germ-line mutations of BRCA1 have distinct clinical and pathological features as compared with sporadic ovarian cancers. METHODS: We reviewed clinical and pathological data on patients with primary epithelial ovarian cancer found to have germ-line mutations of BRCA1. Survival among patients with advanced-stage cancer and such mutations was...

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PMID: 8875917
DOI: 10.1056/nejm199611073351901

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Related research

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Clinical and Pathological Features of Ovarian Cancer in Women with Germ-Line Mutations of<i>BRCA1</i>PMID 8875917Read ↗

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"BRCAness" syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations.Semantic proximity Read ↗

BRCA1-related papillary serous carcinoma of the peritoneum has a unique molecular pathogenesis.Semantic proximity Read ↗

One in 10 ovarian cancer patients carry germ line BRCA1 or BRCA2 mutations: results of a prospective study in Southern Sweden.Semantic proximity Read ↗

Histopathology of familial ovarian tumors in women from families with and without germline BRCA1 mutations.Semantic proximity Read ↗

BRCA1 germline mutations and polymorphisms in a clinic-based series of ovarian cancer cases: a Gynecologic Oncology Group study.Semantic proximity Read ↗

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BRCA1 Immunohistochemistry in a Molecularly Characterized Cohort of Ovarian High-Grade Serous CarcinomasSemantic proximity Read ↗

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