Article
Non-heritable change of a spirochaete's phenotype by decoration of the cell surface with exogenous lipoproteins.
Molecular microbiology - 1 Apr 2001
Bunikis J, Mirian H, Bunikiene E, Barbour A G
Abstract excerpt
Genetic transformation of Borrelia spp. is limited in development and has found application in only one species. For a non-genetic approach for manipulating the phenotype of these spirochaetes, we determined whether exogenous recombinant lipoproteins would incorporate in the cell's outer membrane. Using unlabelled or 125I-labelled Osp proteins, Osp-specific monoclonal antibodies, proteinase K and formaldehyde as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
