Article
Borrelia burgdorferi lipoproteins are secreted to the outer surface by default.
Molecular microbiology - 1 Mar 2006
Schulze Ryan J, Zückert Wolfram R
Abstract excerpt
Borrelia spirochaetes are unique among diderm bacteria in their abundance of surface-displayed lipoproteins, some of which play important roles in the pathogenesis of Lyme disease and relapsing fever. To identify the lipoprotein-sorting signals in Borrelia burgdorferi, we generated chimeras between the outer surface lipoprotein OspA, the periplasmic oligopeptide-binding lipoprotein OppAIV and mRFP1, a monomeric...
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