Article
Effects of human fibroblasts from myelometaplasic and non-myelometaplasic hematopoietic tissues on CD34+ stem cells.
International journal of cancer - 15 May 2001
Brouty-Boyé D, Briard D, Azzarone B, Le Bousse-Kerdilès M C, Clay D, Pottin-Clémenceau C, Jasmin C
Abstract excerpt
Fibroblasts demonstrate different phenotypes and functions according to the tissue of origin and its physiopathologic state. We previously showed that fibroblasts isolated in culture from myelometaplasic (MM) spleen differed phenotypically from fibroblasts from normal bone marrow (BM). We compared the influence of each type of fibroblasts on the behavior of CD34+ stem cells. Expansion of nucleated cells was...
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