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Article

Alternative origins of stroma in normal organs and disease

10 Dec 2011

Abstract excerpt

Stromal fibroblasts are a new prospective drug target. Mesenchymal stromal cells (MSCs) and monocyte-derived stromal cells, also known as fibrocytes, are distinct fibroblastic populations derived from separate lineages. Mesenchymal and myeloid fibroblast progenitors are multipotent, serve as progenitor cells in animal models, and are implicated in several diseases. In addition, epithelial-mesenchymal transition...

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PMID: 22209011
DOI: 10.1016/j.scr.2011.11.005

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