Article
Identification of a Hematopoietic Cell Dedifferentiation-Inducing Factor.
Journal of cellular physiology - 1 Jun 2016
Li Yunyuan, Adomat Hans, Guns Emma Tomlinson, Hojabrpour Payman, Duronio Vincent, Curran Terry-Ann, Jalili Reza Baradar, Jia William, Delwar Zahid, Zhang Yun, Elizei Sanam Salimi, Ghahary Aziz
Abstract excerpt
It has long been realized that hematopoietic cells may have the capacity to trans-differentiate into non-lymphohematopoietic cells under specific conditions. However, the mechanisms and the factors for hematopoietic cell trans-differentiation remain unknown. In an in vitro culture system, we found that using a conditioned medium from proliferating fibroblasts can induce a subset of hematopoietic cells to become...
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