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Article

Comparative binding energy (COMBINE) analysis of influenza neuraminidase-inhibitor complexes.

Journal of medicinal chemistry - 15 Mar 2001

Wang T, Wade R C

Abstract excerpt

Neuraminidase is a surface glycoprotein of influenza viruses that cleaves terminal sialic acids from carbohydrates. It is critical for viral release from infected cells and facilitates viral spread in the respiratory tract. The catalytic active site of neuraminidase is highly conserved in all type A and B influenza viruses, making it an excellent target for antiinfluenza drug design. Indeed, neuraminidase...

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PMID: 11300878
DOI: 10.1021/jm001070j

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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