Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hsp90 chaperone complexes are required for the activity and stability of yeast protein kinases Mik1, Wee1 and Swe1.

European journal of biochemistry - 1 Apr 2001

Goes F S, Martin J

Abstract excerpt

The Wee1 protein kinase negatively regulates entry into mitosis by mediating the inhibitory tyrosine phosphorylation of Cdc2-cyclin B kinase. The stability and activity of Wee1 from the fission yeast Schizosaccharomyces pombe is critically dependent on functional Hsp90 chaperones. Here we identify two related tyrosine protein kinases, Mik1 from fission yeast and its Saccharomyces cerevisiae homolog Swe1, as Hsp90...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotics, Antineoplastic
Share to Benzoquinones
Share to Cyclophilins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HSP90 Heat-Shock Proteins

Share to Lactams, Macrocyclic

Share to Peptidylprolyl Isomerase

Share to Quinones

Share to Schizosaccharomyces pombe Proteins

Source

Identifiers

PMID: 11298745
DOI: 10.1046/j.1432-1327.2001.02105.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hsp90 chaperone complexes are required for the activity and stability of yeast protein kinases Mik1, Wee1 and Swe1.PMID 11298745Read ↗

Genetic interactions between Hsp90 and the Cdc2 mitotic machinery in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

A role for Hsp90 in cell cycle control: Wee1 tyrosine kinase activity requires interaction with Hsp90.Semantic proximity Read ↗

Cdk1-dependent regulation of the mitotic inhibitor Wee1.Semantic proximity Read ↗

Drosophila wee1 has an essential role in the nuclear divisions of early embryogenesis.Semantic proximity Read ↗

Determinants of Swe1p degradation in Saccharomyces cerevisiae.Semantic proximity Read ↗

Cdk1 and SUMO regulate Swe1 stability.Semantic proximity Read ↗

Curriculum Vitae of WEE2 Kinase in Homeostasis and Diseases: A Systematic Review.Semantic proximity Read ↗

The checkpoint kinase Hsl1p is activated by Elm1p-dependent phosphorylation.Semantic proximity Read ↗

Hsp90 protein in fission yeast Swo1p and UCS protein Rng3p facilitate myosin II assembly and function.Semantic proximity Read ↗

Yeast Pdr13p and Zuo1p molecular chaperones are new functional Hsp70 and Hsp40 partners.Semantic proximity Read ↗

Functional and physical interaction between yeast Hsp90 and Hsp70.Semantic proximity Read ↗

Wee Kinases, Big Impact: Wee and Myt Kinases as Critical Regulators of Meiotic ProgressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.