Article
Yeast Pdr13p and Zuo1p molecular chaperones are new functional Hsp70 and Hsp40 partners.
Gene - 17 Oct 2000
Michimoto T, Aoki T, Toh-e A, Kikuchi Y
Abstract excerpt
The deletion of the TOM1 gene encoding a putative ubiquitin ligase causes a temperature sensitive cellular growth in Saccharomyces cerevisiae. The arrested cells exhibit pleiotropic defects in nuclear division, maintenance of nuclear structure and heat stress responses. We previously identified a zuo1 mutation as an extragenic suppressor of the tom1 mutant. ZUO1 encodes a DnaJ-related Hsp40. Here we show that a...
Topics
- DNA-Binding Proteins
- Fungal Proteins
- Gene Dosage
- HSP40 Heat-Shock Proteins
- HSP70 Heat-Shock Proteins
- Heat-Shock Proteins
- Homeodomain Proteins
- Molecular Chaperones
- Mutation
- Phenotype
- Protein Binding